The Little-Known KEY to Strong, Pain-Free Joints: Healthy Chondrocytes

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chondrocytesYou know how important cartilage is for healthy joints, right?

It’s the cartilage that acts as a cushion so your bones don’t rub together every time you twist, bend or move. When that cartilage deteriorates, as it often does with age or due to repetitive stresses or injury — ouch! Joint pain is virtually a given.

There’s a good chance, however, that you haven’t heard about chondrocytes, which are the cells that form the cartilage in your body. Chondrocytes are also responsible for the biosynthesis of three crucial factors for joint health: collagen type II, hyaluronic acid (HA, which acts as a cushion and lubricant in your joints), and chondroitin sulfate, which we’ll explain below.

In people with severe knee pain, autologous chondrocyte implantation (ACI) is a recognized medical treatment that involves culturing chondrocyte cells (sourced from cartilage elsewhere in your body) and then implanting them into the damaged area. The idea is that by injecting chondrocytes back into the cartilage, it may help to repair and heal the area by essentially growing new joint cartilage.

Chondrocytes are obviously essential for healthy joint function, as they are the only cells that produce cartilage tissue. However, your body must have the proper building blocks available in order for chondrocytes, and thereby also your cartilage, to flourish.

If you have joint pain, that’s a sign that your body is not meeting the nutritional requirements necessary for cartilage to be sustained, let alone repaired and strengthened.

How to Stimulate Your Body to Produce More Chondrocytes — Hydrolyzed Collage Type II

ACI surgery is not the only way to get your body to build new cartilage. A far less invasive option is to supplement with hydrolyzed collagen type II. By strengthening cartilage and replenishing the synovial fluid that helps lubricate your joints, hydrolyzed collagen improves joint comfort and mobility. Hydrolyzed collagen is important, in particular, because it contains glycosaminoglycans (GAGs) such as hyaluronic acid (HA) and chondroitin sulfate, which help promote joint cushioning and lubrication.

Further, hydrolyzed Collagen Type II may even help to rebuild cartilage because it stimulates the production of chondrocytes.

Only hydrolyzed collagen stimulates type II collagen biosynthesis, which stimulated the cartilage-making chondrocytes; undenatured collagen failed to do so according to one study[i] (collagen in its native or unhydrolyzed form has a large molecular structure that is difficult for your body to use and absorb). Type II collagen is important because it is specific for the articular, or joint, cartilage (type I collagen is found in your bones, skin, tendons, blood vessel walls and organs).

According to BioCell Collagen:[ii]

“Residing exclusively in the cartilage, the chondrocytes are responsible for the biosynthesis of collagen type II, HA, and chondroitin sulfate. Hydrolyzed collagen type II … has been shown to stimulate these cells to synthesize new collagen type II, suggesting that … [it] may help in the regeneration of degraded cartilage.”

Two Additional Nutrients for Healthy Chondrocytes

  1. Glucosamine is found naturally throughout your body, but especially in your cartilage. In your joints, it acts as a building block and helps provide structure to your cartilage while maintaining healthy joint function and mobility. Glucosamine helps your body’s chondrocytes to repair damaged cartilage and slow the rate of cartilage breakdown.[iii]
  2. Chondroitin sulfate is another building block necessary for chondrocytes to build new cartilage, and is naturally found in the cartilage around your joints. It is known to work synergistically with glucosamine and has been shown to improve symptoms of joint pain[iv] and possibly even reverse joint deterioration.

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