What makes Heal-n-SootheŽ better than NSAID's and other pain-relieving formulas?

Here are 7 great reasons you should ditch your prescription pain medication and test out our 100% natural solution instead...

Reduces pain, inflammation and swelling WHILE healing the source of the pain. NSAID's harm your body instead of heal it.

Dissolves pain in minutes with 12, 100% natural, inflamation-fighting ingredients. Other's don't.

100% safe / no side effects unlike NSAID's which put over 100,000+ people in the hospital each year and kill over 16,000+ people!

Boosts your immune system by cleansing your blood and killing viruses and bacteria so you get sick less often!

Improves joint mobility and flexibility by reducing stiffness-causing fibrin. Other's don't.

Scientifically proven to work through medical research studies (76 of them are listed at the very bottom of this page!)

Your first bottle is FREE when you fill out the form to the right...

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Mother Nature's Answer For
Safely Fighting Inflammation...

It's called Systemic Enzyme Therapy and it has been used in numerous countries throughout the world for over 50 years.

The word systemic means whole body and systemic enzymes operate throughout your body in every system and organ. Enzymes, which are known as biocatalysts - something that makes something else work or work faster.

Enzymes are basically the main line of defense against inflammation. Enzymes are not anti-inflammatory drugs but rather reduce inflammation by neutralizing the bio-chemicals of inflammation to levels where the creation, repair and regeneration of injured tissues can take place.

Reducing inflammation can have immediate impact on improved heart health, cancer prevention and recovery, and Alzheimer's prevention. It also helps speed up recovery from sprains, strains, fractures, bruises, contusions, surgery -- and arthritis.

Unlike NSAID's which may give only temporary relief and do not fix the underlying cause of the problem, systemic enzymes work to reduce the inflammation and promote healing without any side effects.

Here are just a few examples…

A study published in the Journal of Medicine, Science, Sports and Exercise found that "proteolytic enzymes have therapeutic effects in the treatment of inflammation and soft tissue injuries."

Another study done by the Institute of Cancer Research in Vienna found that "a combination of proteolytic enzymes and herbs were effective in treating rheumatoid arthritis and reducing TGF-b which is known to be present in the blood when there is cancer."

And in a study done by Dr. Nicholas Gonzales, which was published in the medical journal, Nutrition and Cancer, Dr. Gonzales compared systemic enzyme therapy against a new cancer drug, Gemcitabine. He found that 5 out of 11 patients treated with systemic enzymes lived two years or longer and not a single patient of the 129 treated with the drug lived more than 19 months!

So, as you can see, not only is systemic enzyme therapy safe and effective, but also it's often more effective than the drugs.

In Addition To Reducing Inflammation
and Eliminating Pain, Enzymes Also...


Break down scar tissue and fibrosis – Fibrosis is scar tissue that builds up in our bodies and over time creates some much restriction and strain on our organs that they can no longer function.

Well, systemic enzymes eat away that excess build up of fibrin and scar tissue. Doctors throughout Europe and Asia have been using them for over 50 years to remove scar tissue from surgical wounds, kidney fibrosis, pulmonary fibrosis and in numerous other scenarios.

Cleanse the blood – systemic enzymes also clean the blood of excess fibrin that causes the blood to thicken, which sets you up for clots, which can cause heart attack or stroke. Enzymes also help take some of the strain off of the liver by keeping the blood clean and not allowing it to thicken beyond normal.

WARNING: If you are a hemophiliac or are taking prescription blood thinners, it's strongly recommended that you consult with your healthcare professional before considering systemic enzyme therapy.

Maintain a healthy immune system – enzymes are adaptogenic and they work to restore the body's balance. When the immune system is low and we become more susceptible to infections, the enzymes clean the blood to help fight off infection. And if the immune system is too ramped up, as with auto-immune diseases, the enzymes work to tone down the immune system and eat the antibodies that are attacking the healthy tissue.

Red Blood Cells getting stuck in and amongst fibrin. This happens when there aren't sufficient proteolytic enzymes in the blood stream.

Fight and kill viruses – another amazing and powerful effect enzymes have is that they seek out and kill proteins that have viruses attached to them. Systemic enzymes have shown to be very effective in treating and preventing viral infections.

Systemic enzymes truly are one of nature's most powerful natural remedies.


If you suffer from any sort of ache or pain, or if you just want to get and stay as healthy as possible, I urge you to consider systemic enzymes. They have been used to safely and effectively eliminate pain and inflammation from all sorts of conditions like arthritis, colitis, back pain, sciatica, joint pain, heart disease, cancer and more.

After years of research and testing, we have created the most powerful systemic enzyme formulation in the world. But we didn't stop there, we also added numerous other herbs, vitamins and nutrients that have been proven to have anti-inflammatory effects and together, they make one extremely effective combination called

This powerful inflammation fighting formula includes:


Proteolytic Systemic Enzymes - Research indicates these enzymes work throughout your entire body to help it fight inflammation, breakdown scar tissue, cleanse the blood and also boost cardiovascular, respiratory and immune function.


Bromelain -  This special natural compound, which is extracted from pineapple, contains several proteolytic enzymes that have been shown to short-circuit multiple pain pathways in the body.


It has been studied extensively since it's discovery in 1957 and hundreds of studies have shown it to reduce inflammation, reduce and prevent swelling and remove waste and toxins from the blood.


Turmeric Extract - is taken from the dried root of the plant and it has been used to treat a wide range of ailments for thousands of years.


Studies have shown that it reduces inflammation by blocking both the COX-2 and 5-LOX enzymes which create pain. In addition, Turmeric's antioxidant powers work to seek out and destroy free radicals in the body which contribute to pain and swelling.


Papain - contains a wide range of proteolytic enzymes and works by breaking down proteins. In studies it has been shown to be effective in the treatment of numerous conditions such as diabetes, herpes, cancer and digestion issues like bloating and chronic indigestion. Papain has also been shown to attack tumor cells and boost the immune system.


Boswellia Extract - One of the most widely used herbs in Indian medicine, it has been used for centuries by traditional Indian healers to reduce pain and inflammation. Hundreds of studies have been done proving it's effectiveness and in addition to being a powerful and safe, natural anti-inflammatory, Boswellia has also been shown to support healthy blood circulation.


Scientifically Proven Relief!

The pain reducing powers of  Heal-n-SootheŽ have been proven to be highly effective in numerous clinical studies.

For example, in one study, 77 patients taking 400mg/day of Bromelain experienced significant reduction in pain and swelling.

A recent study done at the prestigous Sloan-Kettering Cancer Research Center in New York found that Turmeric was more safe and precise than asprin in stopping inflammation by shutting down the COX2 enzyme responsible for pain. But Turmeric caused none of asprin's typical gastrointestinal irritation.

In a randomized, double-blind, placebo controlled study, 30 patients received 333mg, 3x a day of Boswelia. The group who received the Boswelia had a significant reduction in pain and swelling and experienced an increase in joint mobility and flexibility as compared to the placebo group.

And these are just a few of the hundreds of studies that have been done to prove the effectiveness of these ingredients.


Rutin - Found naturally in a variety of plants and fruits, this flavanoid has been shown to have a strong anti-inflammatory effect due to it's powerful anti-oxidant activity.


Mojave Yucca (root) - contains yuccaols and resveratrol which have been studied to potentially reduce inflammation. Additionally, yucca may have antioxidant activity. Yucca may be beneficial for anti-inflammatory support, immune support, as well as digestive support.


Ginger Extract - Used for over 2,500 years in Asia, Ginger has been used to treat nausea and to reduce pain and inflammation. It works by decreasing the amount of prostaglandins, which are what cause you to feel pain.


Devil's Claw - another time-tested natural pain reliever, Devil's Claw has been used for hundreds if not thousands of years in Africa. Numerous studies have proven it's effectiveness in reducing pain and inflammation. In fact, one study found that Devil's Claw was as effective in treating arthritis pain as common drug, phenylbutazone.


L-gluathione - a compound found in nearly all forms of life, L-gluathione protects the body from oxidative damage by acting as a buffer.


Vitamin E - This fat-soluble vitamin is an essential nutrient for humans and is known for it's powerful anti-oxidant properties. Vitamin E has been shown to be beneficial in numerous situations and conditions such as controlling high blood pressure, maintaining healthy and balanced cholesterol levels, boost immune system function and improving circulatory conditions, skin health, memory and more.


Citrus Bioflavanoids - aid in the absorption of vitamins and act as important anti-oxidants. Citrus Bioflavanoids inhibit collagenase and elastase, the enzymes responsible for the breakdown of connective tissue. In addition to protecting connective tissues, they also protect against free radical damage.


On their own, each of these ingredients have been proven through both clinical studies and thousands of years of use, to be safe and effective. But together, they work synergistically to quickly reduce inflammation and pain. And unlike prescription and over-the-counter NSAID's, Heal-n-SootheŽ works without the dangerous and harmful side effects.

Heal-n-SootheŽ not only has the most powerful combination of natural anti-inflammatory and pain relieving ingredients, but it also has the strongest and highest potency of any proteolytic enzyme formulation available!

And, unlike most supplement manufacturers who will call it a "proprietary blend" and don't say how much of each is included, we show you exactly how much of each ingredient is in the product.

Not only can you not find a more effective and powerful supplement, but you can't even purchase an enzyme formula like this at your local drug store.

Try Heal-n-SootheŽ Now For FREE!
$59 FREE!

Look, I know your skeptical. You should be. Look at all the big drug companies who are lying to you each and every day trying convince you that their dangerous (sometimes deadly!) drugs are safe.

So I thought there's no better way for you to find out if Heal-n-SootheŽ will work for you, than having you try it. And that's why I'd like to send you a 90 count bottle, a one-month supply for free. You just pay the shipping and handling. This is a real $59 value and as you can imagine, I can't offer this forever so I urge you to grab your free bottle today.

STEP 1: Tell Us Where to Ship Your FREE Bottle
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WARNING: Persons who suffer from medical conditions or who are taking medications should consult their physician prior to taking this product. This product may thin the blood and may not be appropriate for all persons. Do not take this product if you know or suspect that you are allergic to pineapple, papaya, or any ingredients in this product. As with all dietary supplements, those who are pregnant or nursing should consult their physician prior to taking this product.

Every week we receive dozens of great stories from people who were finally able to dump their pain meds after taking Heal-n-SootheŽ. But I don't expect you to take my word for it... take a look at these:

Here's What People Are Saying...

Here's my story:

I've had orthopedic problems since I was 7 years old. I figured up that over the last 31 years (I'm 38 now), I've had a total of 14 surgeries---6 of them knee surgeries and 1 foot surgery---plus a broken pelvis and sprained SI joint from a past car accident. After the foot surgery 10 years ago, the doctor decided I would benefit from taking Celebrex. It helped a good bit, but I haven't been pain-free at any point in that time. Recently, after being diagnosed with severe arthritis in one knee and moderate arthritis in my foot, the doctor doubled my dosage of Celebrex. I couldn't discern any improvement on the new dosage. Also, I began getting concerned about the possibility of the prolonged usage of this drug causing liver damage. I have had blood tests every 6 months to monitor the health of my liver, and so far no damage has been done. However, it finally hit me that the doctors probably wouldn't take me off the Celebrex until I got a negative report on my blood tests---which would mean the damage had already been done!

I decided it was time to at least try life without this medication. I tapered off my dosage, and decided to try your Heal-n-SootheŽ. After a week off the medication, I felt worse than ever as my body was "detoxing" from Celebrex. Another week later, after several days on Heal-n-SootheŽ, I felt a little better. I have now been taking Heal-n-SootheŽ for 30 days, and I feel the same as I did while taking the double dosage of Celebrex. I have hope that after more time on Heal-n-SootheŽ, I will feel even better---and I like that right now I'm getting at least the same, if not yet better, anti-inflammatory effect from natural enzymes, rather than from a chemical that could potentially harm my liver.

Thanks so much!

Kaye Whitlock
stay-at-home Wife & Mom to 4 kids

"I can't imagine life without Heal-n-SootheŽ!"

"I really think the Heal-n-SootheŽ have been doing a great job on me! I have just started my 2nd month of using them and for right now I can't imagine life without them! I do feel better. Thanks for a great product."

Sandy Underwood 

"This stuff ROCKS! I felt improvement the first day!
It eliminates aches and pains!"

"As a serious student of martial arts, my body has taken a beating and no matter how good you are about taking care of yourself, we all have aches and pains. Well, I have NEVER experienced anything that works as well as Heal-n-SootheŽ... this stuff rocks!

I felt improvement the very first day and not only does it eliminate aches and pains, but my flexibility has also increased quite a bit. Now I take it after every hard training session to make sure I don't wake up sore, stiff and achy the next morning. If you have any aches and pains I suggest you give this stuff a shot!"

Otis Berry
Germantown, Maryland

Chief Krav Maga Instructor and One of Only 30 Krav Maga Black Belts in The United States

"WOW! Huge difference … I stopped taking painkillers!"

"All I can say is a big WOW and thank you.  I have only been taking them for 4 or 5 days, but have noticed an huge difference.  I stopped taking my strong painkillers, Co Codemal (the strongest) and Dihydrocodine, which I was taking every day and the full limit allowed in a day.I feel "almost" normal again." 

From a very very grateful,
Angela Jaggs (England, UK)

"Thank You!"

Dear Jesse

"Thank You for all the Emails you have been sending me since I enrolled in the "Lose The Back Pain System"

I also purchased the Heal-n-SootheŽ Capsules at the very Welcome Price!

I stopped taking all NSAIDS Immediately (which I have been taking for five years) and started taking the Heal-n-SootheŽ Capsules - To my delight about half the burning sensations in the front and sides of my shins disappeared by the second day of use.

The awful debilitating Cramps in my Calves and Feet ceased almost altogether - Leaving me now to contend with ' Only ' Sciatica in my right buttock and leg - numbness in both my feet and toes and pains in the soles of my feet and heels, like standing on Golf Balls - which in itself is a Great improvement - So I will continue with a further course of the Heal-n-SootheŽ Capsules :-)

We have enjoyed Every moment of the Video and Audio and the Emails and also the Further Links - Our heads are Spinning - with glee at the prospect of Help may yet be at hand !!

Best Wishes to You All

Chris and John

"My pain and inflammation went down in just 2-days!"

"I have been taking Heal-n-SootheŽ, for 3 weeks now. I must say at first I was very skeptical, I was thinking "How can this really help if my medication the doctor gave me does not work??!" But sometimes you reach a point or a day where the pain is so bad, that you will try anything, any price, just anything that might have a slight chance of getting rid of your pain...So I did.

And I was pleasantly surprised, after about 2-3 days on the activation dose, I noticed reduced inflammation, and my pain in my leg reduced. At first I was thinking "Maybe its just the nice weather we have here in the U.K at the moment?" : )

I realized that it must be the Heal-n-SootheŽ, because I missed one days dosage and the next day I felt really bad : ( It took 2 days after to get things back on track, and I make sure I do not forget them now. It means that I am able to stretch further and more often as the other post stated, and walk more. I'm a believer that you "Can't put a price on your health"."

Dan Monahan, England

"I can walk to the store again without pain!"

I tried the Heal-n-SootheŽ free bottle that I received. You were right! It worked really good and I do feel much better. My back pain is much improved and since taking the Heal-n-SootheŽ I can walk the 2 blocks to the grocery store, spend an hour gathering groceries, then walk back home with my cart of groceries. I don't even have to sit down or lie down when I get home and my back is not hurting. Not only that, but I seem to have more energy and generally feel better. Heal-n-SootheŽ is great!

I really believe that if I continue with the Lose the Back Pain exercises and keep working on my weight problem, I will soon not have to rely on pills of any kind. I am so glad I found and purchased your Lose the Back Pain System and Heal-n-SootheŽ. It has exceeded my expectations. I am improving rather slowly, but I AM STEADILY IMPROVING, thanks to you guys and the rest of your group.

Barbara Adams
San Diego California area

"Thank you!!! Heal-n-SootheŽ gave me a new PAIN FREE life!"

Hey Jesse:
Just a note to tell you how much your Heal-n-SootheŽ has helped me in just a week. It is working very well. I have a crooked spine, and sciatic nerve problems. Your product has given me a whole new life of PAIN FREE. I can actually golf now. Please keep sending every month. It has made a big difference in my life. Thank You... Thank you !!!!!

Sandra Marginet, Michigan

"My back-pain subsided to almost nothing — I don't have to 'play through the pain' anymore! Thank you so much!"

"Within the first week...

Recurring back pain from previous soccer seasons affected me again in August when I began my Fall soccer season. At first I was playing through the pain and then I started taking Heal-n-SootheŽ. Within the first week I noticed a significant decrease in the amount of pain I felt.

I have been taking them now for nearly two months and over the course of these two months my back pain has subsided to almost nothing and I have been able to continue playing soccer all season. I truly believe that Heal-n-SootheŽ has enabled me to get to where I am today which is playing pain-free.

Thanks, That is my story and thank you so much for your help!"

Lisa Brown

"WOW! What a difference!"

"Hi Steve, I just wanted to tell you guys at the HealthyBack Institute what a geat product you have in this Heal-n-SootheŽ. I have been taking it for about 4 months now and all I can say is, WOW, what a difference! I wish I had known about Enzyme therapy sooner. I noticed a difference right away and now when I hit it hard on the tennis court or in any other activity I increase the dosage for a few days after and my recovery is almost instant. All I can say is thank you for the help and support and send me some more!"

Nicholas Batt

"An amazing 'serendipitous' benefit ..."

"Thank you so much for the advice. I just wanted to tell you about an amazing, "serendipitous" benefit I've gained from taking Heal-n-SootheŽ. While they truly help my back pain when I double the recommended dose, I've found that they've practically "cured" an ongoing, life long, severe digestive problem.

I was at the point where I couldn't even drink water without serious pain, bloating and gas. My reflux was so bad that I had to sleep sitting up. While I do take other digestive enzymes and they help somewhat, they have not controlled the problem sufficiently. Recently, it has gotten so bad that I've been forced to go through the usual battery of costly and intrusive tests...only to find once again...NOTHING. Then, one day about a week ago, I decided to double my Heal-n-SootheŽ dosage because of increased back pain.

About 3 days later, I noticed that my digestive problems were ALL so much improved that I practically forgot about them. I can only attribute the improvement to the Heal-n-SootheŽ because I have not taken any other supplements.

Thank you, thank you, thank you"

Gina Ripple

"I'm off prescription Celebrex because of Heal-n-SootheŽ.
My heartfelt thanks!"

"YOU GET IT" was a comment I recently received from Steve Heffron, after placing a call to inquire about questions I had regarding "Heal-n-SootheŽ" and "Lose The Back Pain". Steve spent considerable time with me answering my questions and offering suggestions.

I "get it" because of the considerable research you put into both the enzymes and the muscle imbalance issue. Once I reviewed the books and DVD's, did my assessment and began the stretches, it occurred to me that this is the most common sense approach to healing my body. Why do so many of the professionals not "get it"?

I had convinced myself that taking Celebrex may cause side effects which could endanger my life, but was willing to take the risk for the sake of "quality of life". I am happy to report I no longer take Celebrex, once the only drug that would allow me to function "normally" by blocking the pain. The Heal-n-SootheŽ reduces the inflammation to a point where I can now look forward to a productive day, plan trips and live with about 80% less pain. I am currently working on the other 20% as I gradually, at my own pace, address the muscle imbalances and do the stretches as recommended in the Lose the Back Pain System.

I now apply what I have learnt about muscles imbalances on a daily basis to avoid triggering spasms.

It took me 4 and half years of trial and error before I found your website. Another 2 months of procrastination, scepticism, and reading your articles and newsletters before I finally decided to order the Lose The Back Pain System and the Heal-n-SootheŽ. So glad I did, wish I had done it sooner!

Heartfelt thanks Jesse and Steve. I hope you continue to help others as you have helped me.

Christine M.

P.S. Love the new website...

"As a pharmacist I've seen it all. Heal-n-SootheŽ is as effective as prescription anti-inflammatories, but MUCH SAFER."

"As a pharmacist with a keen interest in natural supplements I can safely say I've seen it all. But for patients with pain - who are looking for an answer outside of dangerous prescription medications - I have only a handful of recommendations. Heal-n-SootheŽ is on that short list.

It's not only as effective as prescription anti-inflammatories, but is much safer. And, unlike other supplements on the market, Heal-n-SootheŽ really is free of any fillers or colorants. It truly is all natural.

The point is this: if you're sitting on the fence about other options to treat your pain you owe it to yourself to give Heal-n-SootheŽ a fair shot. You'll be happy you did."

Dr. Curtis Alexander, Registered Pharmacist
Doctor of Pharmacy


No More PMS Pain

"I was stuck in a 3 day meeting out of town and started my period unexpectedly. There I was miles from home with no easy way to get my usual pain relief medicine. I quietly asked around and a friend gave me some of her Heal-n-SootheŽ. "Something is better than nothing I thought" But boy was I wrong... This something was FANTASTIC. Usually it hurts so much I find myself totally distracted or I'm at least very uncomfortable the whole 5 days even with traditional over the counter pain relief supposedly designed for that unpleasant week every month. But with this I felt great... no pain and I can't believe how fast it worked! I now have two bottles on stand by... one for the office and one for the house."

Christa Trantham, Dallas Texas

Still Have Questions?

Heal-n-SootheŽ Frequently Asked Questions



Q: How often should Heal-n-SootheŽ be taken?

A:   Heal-n-SootheŽ should be taken at least once per day and can be taken as often as three times per day on empty stomach: 30 minutes before or 60 minutes after meals for best results. Some people find that a single dose before bed works best.

Begin by taking 2 capsules twice per day or 4 capsules once per day. If you do not feel a reduction in pain at that dosage, experiment with a higher dosage by gradually increasing the dosage by 1-2 capsules per day until you find what works best for you. *

Q: Are there any Side Effects?

A:   Proteolytic enzymes have an excellent safety record, with no significant side effects reported. With any supplement, however, there is always the risk of developing an allergy to one or more ingredients. If this happens, you should discontinue use. *

Q: Is Heal-n-SootheŽ made with any animal product?

A:   NO, Heal-n-SootheŽ is 100% natural and contains NO animal derivatives. *

Q: Can I take Heal-n-SootheŽ with other medications?

A:   Individuals taking any medication should consult physician prior to taking Heal-n-SootheŽ, it is recommended that you wait at least 60 minutes after taking Heal-n-SootheŽ before taking any medications. *

Q: Who should not take Heal-n-SootheŽ?

A:  Persons who suffer from medical conditions or who are taking medications should consult their physician prior to taking this product. This product may thin the blood and may not be appropriate for all persons. Do not take this product if you know or suspect that you are allergic to pineapple, papaya, or any ingredients in this product or suspect that you have an ulcer. As with all dietary supplements, those who are pregnant or nursing should consult their physician prior to taking this product.*

  • Individuals taking prescription blood thinners (Coumadin, Heparin, Plavix)
  • Anyone who will be having surgery in less than two weeks
  • Individuals with known ulcers of the stomach
  • Pregnant or lactating women
  • Individuals currently taking antibiotics
  • Individuals with an allergic reaction to pineapples or papayas
  • Individuals under the age of 13

Q: How long should I take Heal-n-SootheŽ?

A:   Heal-n-SootheŽ can and should be taken daily along with your multi-Vitamin for as long as you want to keep inflammation in check and continued support for soft tissue recovery, improved joint function and maintaining a healthy immune response as well as support to cardiovascular and respiratory function. *

Q: Warning about Side Benefits?

A:   It is possible that you may experience the following effects on the body.

  • For individuals with sinus issues, you may experience some drainage for a short time as the mucus thins and is eliminated from the body. *
  • For individuals with digestive issues, you may experience some gas or loosing of your stool as undigested matter is broken down and eliminated. *
  • For individuals with borderline high blood pressure, as fibrin is eliminated from the body, there will be less resistance on the blood and thus your blood pressure could come down. *
  • For women with Uterine Fibroids, you may experience some vaginal discharge as the Fibroid is broken down and is eliminated. *



Clinical Studies Used In The Research and Development of Heal-n-SootheŽ

  1. G. Klein and W. Kullich, "Reducing Pain by Oral Enzyme Therapy in Rheumatic Diseases," Wien Med Wochenschr 149 (1999): 577-80.

  2. Stone MB, Merrick MA, Ingersoll CD, Edwards JE. Preliminary comparison of bromelain and Ibuprofen for delayed onset muscle soreness management. Clin J Sport Med. 2002 Nov;12(6):373-8.

  3. J. C. Dekkers, L. J. van Doornen, and H. C. Kemper. "The Role of Antioxidant Vitamins and Enzymes in Prevention of Exercise-Induced Muscle Damage, " Sports Med 21, no. 3 (March 1996): 213-38.

  4. Inderst, R.: Systemic enzyme therapy. Journal of Pharmacy 52 (1992).

  5. Ekerot, L. K; Ohlsson, K.; Necking, L.: Elimination of protease-inhibitor complexes from the arthritic joint. In. J. Tissue Reac. VII: 391 (1985).

  6. Miyamoto S, Kawano H, Takazoe K, Soejima H, Sakamoto T, Hokamaki J, Yoshimura M, Nakamura H, Yodoi J, Ogawa H. Vitamin E improves fibrinolytic activity in patients with coronary spastic angina. Thromb Res. 2004;113(6):345-51.

  7. Bounous G, Molson J. Competition for glutathione precursors between the immune system and the skeletal muscle: pathogenesis of chronic fatigue syndrome. Med Hypothesis 53;(4): 347-349

  8. Sen CK. Nutritional biochemistry of cellular glutathione. Nutr Biochem 1997;8:660-72.

  9. Johnston CS, Meyer CG, Srilakshmi JC. Vitamin C elevates red blood cell glutathione in healthy adults. Am J Clin Nutr 1993;58:103-5.

  10. Lenzi A, Culasso F, Gandini L, et al. Placebo-controlled, double-blind, cross-over trial of glutathione therapy in male infertility. Hum Reprod 1993;8:1657-62.

  11. Lands LC, Grey VL and Smountas AA. Effect of a cysteine donor on muscular performance.J Appl Physiol. 87 (4):1381-1385 1999.

  12. Powers SK, JI LL, Leeuwenburgh C. Exercise training-induced alterations in skeletal muscle antioxidant capacity:a brief review. Med. Sci. Sports Exerc. Vol31#7:987-997 1999.

  13. Sen CK. Glutathione homeostasis in response to exercise training and nutritional supplements. Molecular & Cellular Biochemistry. 196:31-42 1999

  14. Julius M, Lang C, Gleiberman L, et al. Glutathione and morbidity in a community-based sample of elderly. J Clin Epidemiol 1994;47:1021-6.

  15. Hagen TM, Wierzbicka GT, Sillau AH, et al. Fate of dietary glutathione: disposition in the gastrointestinal tract. Am J Physiol 1990;259(4Pt1):G530-5.

  16. Favilli F, Marraccini P, Iantomasis T, Vincenzini MT. Effect of orally administered glutathione on glutathione levels in some organs of rats: role of specific transporters. Br J Nutr 1997;78:293-300.

  17. Witschi A, Reddy S, Stofer B, Lauterburg BH. The systemic availability of oral glutathione. Eur J Clin Pharmacol 1992;43:667-9.

  18. Hunjan MK, Evered DF. Absorption of glutathione from the gastro-intestinal tract. Biochim Biophys Acta 1985;815:184-8.

  19. Emele, J. F.; Shanaman, J.; Winbury, M. M.: The analgesic-anti-inflammatory activity of papain. Arch. Int. Pharmacyn. Ther. 159: 126 (1996).

  20. Kameke, E. v.: Inflammation and its treatment with hydrolytic enzymes and rutin. Forum of the General Practitioner (Forum des Praktischen- und Allgemeinarztes) 9 (1981).

  21. Amborse, A. M.; De Eds, F.: Effects of rutin on permeability of cutaneous capillaries. Pharmacol. Esp. Ther. 90: 359 (1989).

  22. Ambrus, J. L. et al.: Absorption of exogenous and endogenous proteolytic enzymes. Clin. Pharmacol. Ther. 8: 362 (1967).

  23. Bartsch, W.: Treatment of zoster with proteolytic enzymes. The Informed Physician 2: 424 - 429 (l974).

  24. Baumhackl, U.; Fordermair, S.: Enzyme therapy in multiple sclerosis. A preliminary report on a multicenter study. General Medicine (Allgemeinmedizin) 19 (4): 169 - 172 (1990).

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